Muscle knots in the Peroneus Tertius are typically located on the outer front of the lower leg, just above the ankle, where the muscle runs from the distal fibula to the base of the fifth metatarsal. These muscle knots often refer pain to the outer ankle, lateral foot, top of the foot, and the heel and can mimic symptoms like ankle sprains, shin splints, or even foot drop. You may feel a tugging or sharp ache when walking or running, especially on uneven surfaces or in unsupportive shoes.