Muscle knots in the Cervical Multifidi are typically located deep along the spine in the neck region, close to the vertebrae, where these small stabilizing muscles help control posture and spinal movement. When muscle knots form here, they can refer pain to the base of the skull, upper neck, and sometimes radiate into the shoulders or upper back, often mimicking tension headaches or neck stiffness. These knots can feel like a deep, aching discomfort and may worsen with poor posture, prolonged sitting, or stress.